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Director Microbiology/Parasitology
Scientist, Protein Biochemistry

Director Microbiology/Parasitology

We are seeking an experienced and motivated Scientist to lead a cross-functional team involved in utilizing novel protein antigens to create vaccines for prevention or immunotherapy for infectious diseases. The successful candidate will be responsible for groups using technologies centered on immunology, molecular biology and biochemistry, while working within a multidisciplinary team setting. The ideal candidate will have significant experience working with bacteria and/or protozoan parasites, with specific emphasis on vaccine development.

Applicants should have an M.D. or Ph.D. in Microbiology, Immunology, Cell Biology, Molecular Biology or equivalent, and at least 8-10 years of experience (industry experience required). Extensive knowledge of animal modeling of disease, evaluation of vaccine efficacy in vivo, and monitoring of cellular immune responses is essential. Familiarity with regulatory aspects associated with vaccine development including IND/BLA filings is a plus. This position requires prior supervisory experience as well as excellent organizational, interpersonal and presentation skills.

Responsibilities for this position include:

  • Directing a group responsible for developing and characterizing protein-based vaccines for prevention of microbial diseases
  • Evaluation and implementation of new technologies for evaluating novel antigens
  • Management of an existing team of Ph.D. and M.S./B.S. scientists
  • Preparation of study reports to support regulatory filings
  • Contribution to product in-licensing efforts
  • Maintenance of external collaborations
  • Drafting and submission of publications, presentations, patent applications, and/or grants
  • Some bench work may be required

Required Skills

  • Significant experience working in vitro and in vivo with bacterial and/or protozoan pathogens, including but not limited to chlamydia, pneumococcus, and plasmodia
  • Experience maintaining external collaborations and alliances
  • Ability to hire, train, and mentor junior staff
  • Must work well within a dynamic and team-oriented start-up environment
  • Track record of creativity and productivity
  • Must possess excellent oral and written communication skills
  • High impact, peer reviewed publications

Education & Experience

  • M.D. or Ph.D. in Immunology, Cell Biology, Molecular Biology or Microbiology
  • Minimum of 8-10 years, 10-15 years preferred
  • Industry experience required, preferably at a vaccine development related company

Interested and qualified for this position? Please click here to email us

 

Scientist, Protein Biochemistry

We are seeking an experienced and motivated Protein Biochemist to lead protein production efforts in support of the identification of novel vaccines for the prevention and treatment of infectious diseases with significant impacts on human health.

Applicants should have a Ph.D. (Biochemistry, Biotechnology, Biomedical Eng., Biochemical Eng.) with 4-5 years experience in protein expression and purification studies. Experience managing protein production projects is desirable.  The individual should possess a strong core competency in protein biochemistry, with experience in state of the art methods used for protein expression, protein purification, and biochemical and biophysical analyses of proteins. This position also requires excellent organizational and interpersonal skills.

Responsibilities for this position include:

  • Expression and purification of proteins to permit the evaluation of protein antigens as potential vaccine candidates
  • Characterization of proteins by biochemical and biophysical methodologies
  • Management of out-sourced protein production by contract research labs

Required Skills

  • Significant experience with protein expression, purification and characterization approaches
  • Familiarity with multiple expression systems including baculovirus, E. coli, and mammalian cells.
  • Expertise with protein purification strategies at various scales using automated and non-automated liquid chromatography techniques such as FPLC and HPLC and analytical techniques such as SDS-PAGE and Western blotting
  • Experience managing and maintaining effective relationships with external labs
  • Ability to work largely independently with appropriate support from peers and management
  • Must work well within a dynamic and team-oriented start-up environment
  • Track record of creativity and productivity
  • Must possess excellent organizational and interpersonal skills

Education & Experience

  • Ph.D. in Biochemistry, Biotechnology, Biomedical Eng., Biochemical Eng.
  • Minimum of 4 years experience in industry required.
  • Vaccine experience preferred.

Interested and qualified for this position? Please click here to email us

 

 

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