Publications

Technology Foundation

Human Vaccines. 2010. Questions for biotechs: Genocea Biosciences. 6:9, 684‐688; September.

Bouwer, H.G., et al., Directed antigen delivery as a vaccine strategy for an intracellular bacterial pathogen. Proc Natl Acad Sci U S A, 2006. 103(13): p. 5102-7.

Hu, P.Q., et al., Escherichia coli expressing recombinant antigen and listeriolysin O stimulate class I-restricted CD8+ T cells following uptake by human APC. J Immunol, 2004. 172(3): p. 1595-601.

Radford, K.J., et al., A recombinant E. coli vaccine to promote MHC class I-dependent antigen presentation: application to cancer immunotherapy. Gene Ther, 2002. 9(21): p. 1455-63.

Higgins, D.E., N. Shastri, and D.A. Portnoy, Delivery of protein to the cytosol of macrophages using Escherichia coli K-12. Mol Microbiol, 1999. 31(6): p. 1631-41.

C. trachomatis

Roan, N.R., et al., Monitoring the T cell response to genital tract infection. Proc Natl Acad Sci U S A, 2006. 103(32): p. 12069-74.

Pneumococcus

Moffitt, K.L., T.M. Gierahn, et al., TH17-based vaccine design for prevention of Streptococcus pneumoniae colonization. Cell Host & Microbe. 2011 Feb; 9(2): 158-165.

Malley R. Antibody and cell-mediated immunity to Streptococcus pneumoniae: implications for vaccine development. J Mol Med. 2010 Feb; 88(2):135-42.

Lu YJ, Forte S, Thompson CM, Anderson PW, Malley R. Protection against pneumococcal colonization and fatal pneumonia by a trivalent conjugate of a fusion protein with the cell wall polysaccharide. Infect Immun. 2009 Mar 2.

Lu YJ, Gross J, Bogaert D, Finn A, Bagrade L, Zhang Q, Kolls JK, Srivastava A, Lundgren A, Forte S, Thompson CM, Harney KF, Anderson PW, Lipsitch M, Malley R. Interleukin-17A mediates acquired immunity to pneumococcal colonization. PLoS Pathogens, 2008, Sep 19;4(9):e1000159