The Innovation & Automation group is looking for a talented and dedicated scientist to join the ATLAS™ screening team, the experimental heart of our immuno-oncology platform. The scientist will join our dynamic group of researchers aiming to develop personalized cancer vaccines by characterizing T cell responses to neoantigens, tumor-associated antigens and antigens from cancer-associated pathogens. In addition to hand-on antigen identification, the candidate will support organizational aspects of the screening workflow for research and clinical applications.
The ideal candidate is a motivated, energetic, detail-oriented person who will carry out experiments with limited supervision and take on project management responsibilities. The successful candidate demonstrates a strong desire to learn new concepts and techniques, has a creative and flexible mind, and lives a do-what-it-takes attitude. Strong communication skills will be key to work well within a dynamic and team-oriented environment.
- Key contributor to the current and next generation of ATLAS™ screening, utilizing various immunological techniques including but not limited to cell sorting, multicolor flow-cytometry, ELISpot, and high-throughput ELISA-based assays.
- Experimental troubleshooting and development of improved workflows suitable for research and clinical application.
- Manage screening throughput based on sample availability.
- Mentor junior members of the team.
- Prepare data summaries and present at various internal company meetings.
- Follow new developments in the field of immune-oncology.
- Maintain literature files as well as accurate laboratory records and notebooks.
- Well-versed in isolation, sorting, culturing, and characterization of primary human PBMCs.
- Experience with common techniques of cellular immunology.
- Familiarity with liquid-handling robots and/or cell imaging techniques is a plus.
- Capacity to adapt and a strong desire to learn new concepts and techniques.
- Excellent record keeping abilities to adequately record and document analytical data.
- Ability to analyze data, draw conclusions, communicate results, and compile technical reports.
- Strong organization skills and ability to multi-task and troubleshoot.
- Excellent communication skills and ability to work effectively in a cross-functional and diverse team.
Education & Experience
- PhD in immunology, cancer biology or a related field with 1-2 years of postdoc experience in an academic or industry setting.
- The ideal candidate will have experience in cell culture and human immunology, specifically in various cell-based assays measuring T cell functionality.
- Familiarity with high-throughput assays and liquid-handling robots are a plus.
- Supervisory experience is preferred.