Bench Scientist, Neoantigen Identification

Position Summary

The Innovation & Automation group is looking for a talented and dedicated scientist to join the ATLAS™ screening team, the experimental heart of our immuno-oncology platform. The scientist will join our dynamic group of researchers aiming to develop personalized cancer vaccines by characterizing T cell responses to neoantigens, tumor-associated antigens and antigens from cancer-associated pathogens. In addition to hand-on antigen identification, the candidate will support organizational aspects of the screening workflow for research and clinical applications.

The ideal candidate is a motivated, energetic, detail-oriented person who will carry out experiments with limited supervision and take on project management responsibilities. The successful candidate demonstrates a strong desire to learn new concepts and techniques, has a creative and flexible mind, and lives a do-what-it-takes attitude.  Strong communication skills will be key to work well within a dynamic and team-oriented environment.

 

Primary Responsibilities

  • Key contributor to the current and next generation of ATLAS™ screening, utilizing various immunological techniques including but not limited to cell sorting, multicolor flow-cytometry, ELISpot, and high-throughput ELISA-based assays.
  • Experimental troubleshooting and development of improved workflows suitable for research and clinical application.
  • Manage screening throughput based on sample availability.
  • Mentor junior members of the team.
  • Prepare data summaries and present at various internal company meetings.
  • Follow new developments in the field of immune-oncology.
  • Maintain literature files as well as accurate laboratory records and notebooks.

 

Required Skills

  • Well-versed in isolation, sorting, culturing, and characterization of primary human PBMCs.
  • Experience with common techniques of cellular immunology.
  • Familiarity with liquid-handling robots and/or cell imaging techniques is a plus.
  • Capacity to adapt and a strong desire to learn new concepts and techniques.
  • Excellent record keeping abilities to adequately record and document analytical data.
  • Ability to analyze data, draw conclusions, communicate results, and compile technical reports.
  • Strong organization skills and ability to multi-task and troubleshoot.
  • Excellent communication skills and ability to work effectively in a cross-functional and diverse team.

 

Education & Experience

  • PhD in immunology, cancer biology or a related field with 1-2 years of postdoc experience in an academic or industry setting.
  • The ideal candidate will have experience in cell culture and human immunology, specifically in various cell-based assays measuring T cell functionality.
  • Familiarity with high-throughput assays and liquid-handling robots are a plus.
  • Supervisory experience is preferred.

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