We are seeking an experienced and highly motivated individual to lead our immuno-oncology vaccine research efforts. As a head of Research, the candidate will develop and execute a comprehensive Research plan for the development of innovative cancer vaccines through exploitation of the company’s proprietary ATLAS™ T cell profiling platform. The position is located in Cambridge MA, and reports to the Chief Scientific Officer. The successful candidate will have a strong background in cellular immunology, cancer biology, and vaccine discovery with extensive management experience. Experience working directly with tumor-specific T cells and previous involvement with contributing to the filing of one or more INDs is required.
Functional competency in vaccine research: The candidate we seek is a Ph.D. or M.D. or with at least ten years of vaccine research experience at a pharmaceutical or biotech company. Though experience or training in immuno-oncology is preferred; our ideal candidate will first and foremost have deep cellular immunology and vaccine expertise. This person must be effective in a small, research-focused, entrepreneurial company where he or she will play a significant role in mapping the research strategy for the company. The ideal candidate will have successfully crafted and implemented research and pre-clinical strategies resulting in successful patent and IND filings. This individual will have a strong understanding of the strategy and content creation to support FDA approval processes for vaccines and a demonstrated track record of anticipating and resolving issues before they arise.
Team leadership: This individual must function well in a highly collegial, entrepreneurial environment. Our candidate will have had significant management responsibilities and a record of accomplishment of leadership success as demonstrated by having recruited a high performing scientific team and leading multi-disciplinary scientific teams through vaccine discovery and candidate nomination, leading to IND.
Scientific and innovative orientation: Among the characteristics of the successful applicant should reside a deep scientific curiosity and interest in understanding and further developing Genocea’s technology and/or inventions to innovate based on emerging data, optimize methods, and where necessary, develop new techniques to capitalize on emerging science. The generation of novel intellectual property and publication in top-tier journals is expected. In addition, the candidate will be expected to critically evaluate external technologies and innovations to support in-licensing and partnering efforts.
Strategic orientation: The candidate we seek can define a Research strategy and be an effective contributor to overall company plans with insight into immuno-oncology vaccine development in the context of financial and market environments. He or she can clearly articulate developing opportunities and threats; and can evaluate options and plans against anticipated commercial and scientific trends.
10+ years of pharmaceutical/biotech industry experience in immuno-oncology vaccine discovery and development
Extensive knowledge of translational T cell immunology with a broad understanding of the current clinical development landscape in immuno-oncology
Basic broad understanding of clinical research
Experience developing animal models to evaluate cancer vaccine candidates
Leadership and management experience coupled with strong interpersonal, oral and written communication skills
Credibility and history of accomplishment as demonstrated with a strong publication and/or patent record
Significant experience working effectively across an organization composed of multidisciplinary teams
Excellence in managing logistical requirements of a complex and interdisciplinary bench science.
A leader and inspirer of people who operates in a collaborative style yet is demanding, objective and results-oriented.
Ability to influence across an organization and to gain the respect of senior management; recognized potential to take on greater responsibilities in the future. The ideal candidate must have collaborated across organizational boundaries to obtain information, seek opinions and even where conflict exists, drive to a decision.
Confidence in decision making within a rapid, flexible and innovative organization.
Clear communicator who can process and position problems proactively within an organization and externally in the regulatory environment. Ability to clearly formulate and deliver appropriate documents (presentations, posters, protocols, papers, study reports).
Personable and collaborative with unquestionable integrity and the vision to help create a world-class vaccine company.