Genocea Biosciences, Inc. is a fast paced, innovative cancer vaccine and cell therapy company based on a unique screening technology (ATLAS™) enabling the identification of novel T cell antigens in samples originating from individuals suffering from cancer or other diseases. To date, this screening technology has delivered a number of completely novel antigens for various intractable infectious diseases and has enabled the initiation of a Phase 1/2a clinical trial to develop a personalized vaccine for solid tumors. The successful candidate for this position will be expected to lead the Discovery team and help broaden the application of the ATLAS™ technology to diverse new therapeutic areas and other immunological functions. The candidate will demonstrate deep mastery and up-to-date knowledge of T cell and innate immune cell biology, as well a detailed understanding and fluency in state-of-the-art high throughput cell-based assays. Extensive automation experience is also required. The candidate should have significant experience managing teams of associate and senior scientists as well as a keen ability to crystalize, communicate and implement strategy at all levels of the company. The ideal candidate should have 10+ years of experience in the pharmaceutical and/or biotechnology industry along with outstanding scientific credentials in the form of an extensive and relevant peer-reviewed publication track record. The candidate will also be an outstanding communicator, both in scientific and project-related strategy.
Leads team responsible for identification of neoantigens for personalized vaccine and cell therapy development
Plans and directs scientific projects aimed at miniaturizing and automating the high throughput identification of T cell antigens and T cell receptors. Identifies and manages necessary resources for achievement of goals.
Ensures that documentation of experimental data meets standards suitable to support publication, FDA submission and patent filing
Assists in the coordination and execution of research collaborations
Hires, manages, trains and mentors technical team consisting of junior and senior scientists. Establishes expectations, defines roles, supports career development and manages performance
Creates vision, delineates, communicates and implements technology development strategy for the entire company
Communicates with Executive team and peers to ensure that technological innovations are fully integrated in the organization
Prior experience (5-10 years) working successfully in a management role. Demonstrated success in managing staff performance. Ability to motivate staff to work effectively and hold staff accountable to individual and departmental goals
Documented topic-specific scientific expertise (peer-reviewed publications, invited speaking engagements)
Extensive experience in high-throughput cell-based assays, T cell biology, molecular biology, and automation. Knowledge of cell imaging and TCR sequencing preferred
Demonstrated skills in data analysis of complex multidimensional datasets, including laboratory and IT automation technologies
Excellent critical thinking, time management and organizational skills.
Excellent written and verbal communication skills, with the ability to present at the highest level.
Ability to engage, sustain and influence effective relationships at the management level.
PhD in immunology, cell biology or related field
10+ years relevant industrial experience
Background in immuno-oncology