Research Associate, Translational Immunology

Position Summary

We are seeking a highly motivated Research Associate to join our translational medicine team. Genocea’s foundational technology, the ATLAS™ platform, is a high-throughput autologous cell assay that discovers T cell antigens thought to be important in fighting a patient’s disease.  ATLAS™ results are used to select validated neoantigens for a patient-specific vaccine. Our lead program, GEN-009, a personalized neoantigen vaccine, is in the clinic. The successful candidate will be an active member of a team that supports the evaluation of immunogenicity and efficacy of oncology vaccines in clinical trials.

The Research Associate in Translational Immunology will assist in design and execution of complex immune-monitoring experiments with human clinical samples for GEN-009, using established and novel procedures. The candidate will be expected to be in the laboratory to perform experiments and clinical testing with other team members. The candidate must have a strong, positive work ethic. The ideal candidate is a dedicated, energetic, detail-oriented person.Demonstrated hands-on experience with cell culture and immunological assays, such as ICS, ELISPOT, cell sorting, immunophenotyping and flow

Primary Responsibilities

  • Testing of Genocea clinical trial samples in immunogenicity assays

  • Design, develop and qualify/validate immunological assays to characterize vaccine therapeutic responses including: ELISPOT, multi-color flow cytometry and intracellular cytokine staining

  • Develop and maintain good working relationships with RAs, scientists, statisticians, computational biologists, and external collaborators as part of a multidisciplinary team.

Competencies

  • Excellent ability to perform hands on experiments and maintain detailed documentation

  • Excellent organizational skills and ability to multi-task and embrace change in an extremely fast-paced environment

  • Independently motivated, detail oriented and good problem-solving ability

  • Ability to work as part of a team, collaborating and communicating effectively with members of other functional groups

  • A sense of humor is essential

Required Skills

  • Prior experience in performing immunoassays and hands on experience in cell culture

  • Ability to work independently and as a part of a cross-functional team with a positive attitude.

  • Strong verbal and written communication skills are required.

  • Ability to analyze data, draw conclusions, communicate results and compile technical reports.

  • Excellent record keeping abilities to adequately record and document analytical data.

  • Capacity to adapt, with a strong desire to learn new concepts and techniques

  • Experience with multi-color flow cytometry and flow data analysis is a plus

  • Excellent computer skills and experience with Microsoft Excel, Flow cytometry data analysis software, and Graphpad Prism are essential

Education Requirements

  • Master’s degree or bachelor’s degree with a minimum of 1 years of experience in biopharmaceutical industry