We are seeking a highly motivated Research Associate to join our translational medicine team. Genocea’s foundational technology, the ATLAS™ platform, is a high-throughput autologous cell assay that discovers T cell antigens thought to be important in fighting a patient’s disease. ATLAS™ results are used to select validated neoantigens for a patient-specific vaccine. Our lead program, GEN-009, a personalized neoantigen vaccine, is in the clinic. The successful candidate will be an active member of a team that supports the evaluation of immunogenicity and efficacy of oncology vaccines in clinical trials.
The Research Associate in Translational Immunology will assist in design and execution of complex immune-monitoring experiments with human clinical samples for GEN-009, using established and novel procedures. The candidate will be expected to be in the laboratory to perform experiments and clinical testing with other team members. The candidate must have a strong, positive work ethic. The ideal candidate is a dedicated, energetic, detail-oriented person.Demonstrated hands-on experience with cell culture and immunological assays, such as ICS, ELISPOT, cell sorting, immunophenotyping and flow
Testing of Genocea clinical trial samples in immunogenicity assays
Design, develop and qualify/validate immunological assays to characterize vaccine therapeutic responses including: ELISPOT, multi-color flow cytometry and intracellular cytokine staining
Develop and maintain good working relationships with RAs, scientists, statisticians, computational biologists, and external collaborators as part of a multidisciplinary team.
Excellent ability to perform hands on experiments and maintain detailed documentation
Excellent organizational skills and ability to multi-task and embrace change in an extremely fast-paced environment
Independently motivated, detail oriented and good problem-solving ability
Ability to work as part of a team, collaborating and communicating effectively with members of other functional groups
A sense of humor is essential
Prior experience in performing immunoassays and hands on experience in cell culture
Ability to work independently and as a part of a cross-functional team with a positive attitude.
Strong verbal and written communication skills are required.
Ability to analyze data, draw conclusions, communicate results and compile technical reports.
Excellent record keeping abilities to adequately record and document analytical data.
Capacity to adapt, with a strong desire to learn new concepts and techniques
Experience with multi-color flow cytometry and flow data analysis is a plus
Excellent computer skills and experience with Microsoft Excel, Flow cytometry data analysis software, and Graphpad Prism are essential
Master’s degree or bachelor’s degree with a minimum of 1 years of experience in biopharmaceutical industry